Sunday, 23 September 2012

Thursday, 19 July 2012

On Reciprocal Best BLAST Hits

In which I narrowly avoid a rant. Reciprocal best BLAST hits can improve the quality of your searching, and are a good way to find candidate orthologues. There's evidence and everything.

Wednesday, 18 July 2012

23 And Me And Me: Part 2

In which the most difficult part of getting yourself genotyped turns out to be dealing with shopkeepers, and I impress the eight-year-old me.

Sunday, 1 July 2012

Dead fish, and multiple-test correction

In which a salmon is resurrected, but not enough to really be significant.  Why finding 20 positive results when your P-value threshold suggests you should only see 10 isn't necessarily anything to be excited about.  And an introduction to Bonferroni and Benjamini-Hochberg multiple test correction.

Saturday, 23 June 2012

The Base Rate Fallacy in Effector-Finding

In which an oft-overlooked bit of genome-mining statistics is considered, and your enjoyment of a holiday could depend heavily on other people's hygiene.